• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly374Valfs*48 (c.1121delG) (Lys373fs); ClinVar=VCV000237940; Zygosity=Heterozygous (PubMed=9715273).
  

PubMed=7761852; DOI=10.1126/science.7761852
Sanford David Markowitz, Jing Wang, Lois Lemmermann Myeroff, Ramon Parsons, Lu-Zhe Sun, James D. Lutterbaugh, Robert S. Fan, Elizabeth Zborowska, Kenneth Wayne Kinzler, Bert Vogelstein, Michael G. Brattain, James K.V. Willson;
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science 268:1336-1338(1995)

PubMed=9715273; DOI=10.1038/sj.onc.1201986
James Richard Eshleman, Graham Casey, Mary E. Kochera, Wallace David Sedwick, Sandra E. Swinler, Martina L. Veigl, James K.V. Willson, Stuart Schwartz, Sanford David Markowitz;
Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53.
Oncogene 17:719-725(1998)

PubMed=11314036; DOI=10.1038/sj.onc.1204211
Eva Forgacs, Jonathan D. Wren, Craig Kamibayashi, Masashi Kondo, Xie L. Xu, Sanford David Markowitz, Gail E. Tomlinson, Carolyn Y. Muller, Adi F. Gazdar, Harold Ray Garner, John D. Minna;
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 20:1005-1009(2001)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)