Cellosaurus cell line RCi001-B (CVCL

Cellosaurus RCi001-B (CVCL_9S42)

Cross-references
Cell line name	RCi001-B
Synonyms	RCi89; Thp3C-9
Accession	CVCL_9S42
Resource Identification Initiative	To cite this cell line use: RCi001-B (RRID:CVCL_9S42)
Comments	From: Pfizer, Inc.; New York; USA. From: Roslin Cells, Ltd; Roslin; United Kingdom. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:10597; SCN9A; Simple; p.Val400Met (c.1198G>A); ClinVar=VCV000538468; Zygosity=Heterozygous (PubMed=27099175).
Disease	Erythromelalgia (NCIt: C34593) Primary erythromelalgia (ORDO: Orphanet_90026)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_9S41 ! RCi001-A
Sex of cell	Male
Age at sampling	>10Y
Category	Induced pluripotent stem cell
Publications	PubMed=27099175; DOI=10.1126/scitranslmed.aad7653 Cao L.-S., McDonnell A., Nitzsche A., Alexandrou A., Saintot P.-P., Loucif A.J.C., Brown A.R., Young G., Mis M., Randall A., Waxman S.G., Stanley P., Kirby S., Tarabar S., Gutteridge A., Butt R., McKernan R.M., Whiting P.J., Ali Z., Bilsland J., Stevens E.B. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Sci. Transl. Med. 8:335ra56.1-335ra56.12(2016)
Cell line collections (Providers)	EBiSC; RCi001-B ECACC; 66540048 - Discontinued
Cell line databases/resources	hPSCreg; RCi001-B SKIP; SKIP002467
Biological sample resources	BioSamples; SAMEA3106040
Encyclopedic resources	Wikidata; Q54949498
Entry history
Entry creation	23-Feb-2016
Last entry update	19-Dec-2024
Version number	16