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Cellosaurus RCi001-B (CVCL_9S42)

[Text version]
Cell line name RCi001-B
Synonyms RCi89; Thp3C-9
Accession CVCL_9S42
Resource Identification Initiative To cite this cell line use: RCi001-B (RRID:CVCL_9S42)
Comments From: Pfizer, Inc.; New York; USA.
From: Roslin Cells, Ltd; Roslin; United Kingdom.
Derived from sampling site: Peripheral blood.
Sequence variations
  • Mutation; HGNC; 10597; SCN9A; Simple; p.Val400Met (c.1198G>A); ClinVar=VCV000538468; Zygosity=Heterozygous (PubMed=27099175).
Disease Erythromelalgia (NCIt: C34593)
Primary erythromelalgia (ORDO: Orphanet_90026)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9S41 ! RCi001-A
Sex of cell Male
Age at sampling >10Y
Category Induced pluripotent stem cell
Publications

PubMed=27099175; DOI=10.1126/scitranslmed.aad7653
Cao L.-S., McDonnell A., Nitzsche A., Alexandrou A., Saintot P.-P., Loucif A.J.C., Brown A.R., Young G., Mis M., Randall A., Waxman S.G., Stanley P., Kirby S., Tarabar S., Gutteridge A., Butt R., McKernan R.M., Whiting P., Ali Z., Bilsland J., Stevens E.B.
Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.
Sci. Transl. Med. 8:335ra56.1-335ra56.12(2016)

Cross-references
Cell line collections EBiSC; RCi001-B
ECACC; 66540048
Cell line databases/resources hPSCreg; RCi001-B
SKIP; SKIP002467
Biological sample resources BioSamples; SAMEA3106040
Encyclopedic resources Wikidata; Q54949498
Entry history
Entry creation23-Feb-2016
Last entry update21-Mar-2023
Version number13