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Cellosaurus IOR/OS14 (CVCL_9990)

[Text version]
Cell line name IOR/OS14
Synonyms IOR-OS14; OS-14; OS14
Accession CVCL_9990
Resource Identification Initiative To cite this cell line use: IOR/OS14 (RRID:CVCL_9990)
Comments From: Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli; Bologna; Italy.
Doubling time: ~48 hours (PubMed=21519327).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
Disease Small cell osteosarcoma (NCIt: C4023)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): PubMed=19787792

Markers:
AmelogeninX
D2S133823
D3S135817
D5S81812
D8S11799,10
D16S53911
D18S5116
D19S43313,14
D21S1132.2
FGA24
SE3314
TH019.3
TPOX9,11
vWA15,17

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Publications

PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X
Katia Scotlandi, Massimo Serra, Maria Cristina Manara, Stefania Benini, Manuela Sarti, Daniela Maurici, Pier-Luigi Lollini, Piero Picci, Francesco Bertoni, Nicola Baldini;
Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.
Hum. Pathol. 27:408-416(1996)

PubMed=9935160; DOI=10.1002/(SICI)1097-0215(19990209)80:4<581::AID-IJC16>3.0.CO;2-O
Stefania Benini, Nicola Baldini, Maria Cristina Manara, Tokuhiro Chano, Massimo Serra, Simona Rizzi, Pier-Luigi Lollini, Piero Picci, Katia Scotlandi;
Redundancy of autocrine loops in human osteosarcoma cells.
Int. J. Cancer 80:581-588(1999)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=21519327; DOI=10.1038/labinvest.2011.72
Alexander B. Mohseny, Isidro Machado, Yong-Ping Cai, Karl-Ludwig Schaefer, Massimo Serra, Pancras Cornelis Wilhelmus Hogendoorn, Antonio Llombart-Bosch, Anne-Marie Cleton-Jansen;
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)

PubMed=23144859; DOI=10.1371/journal.pone.0048262; PMCID=PMC3492335
Stine Henrichson Kresse, Halfdan Rydbeck, Magne Skarn, Heidi Maria Namlos, Ana Heslanyeth Barragan-Polania, Anne-Marie Cleton-Jansen, Massimo Serra, Knut Liestol, Pancras Cornelis Wilhelmus Hogendoorn, Eivind Hovig, Ola Myklebost, Leonardo Andres Meza-Zepeda;
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PLoS ONE 7:e48262.1-e48262.20(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9990
Encyclopedic resources Wikidata; Q54897869
Gene expression databases GEO; GSM879211
Polymorphism and mutation databases Cosmic; 1082499
IARC_TP53; 27025
Progenetix; CVCL_9990
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number20