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Cellosaurus SUP-T13 (CVCL_9973)

[Text version]
Cell line name SUP-T13
Synonyms Sup-T13; SupT13; SUPT13; SUPT-13; Stanford University Pediatric T-cell line 13
Accession CVCL_9973
Resource Identification Initiative To cite this cell line use: SUP-T13 (RRID:CVCL_9973)
Comments Derived from sampling site: Pleural effusion. Cell type=T-cell.
Sequence variations
  • Gene fusion; HGNC; 19124; FIP1L1 + HGNC; 8803; PDGFRA; Name(s)=FIP1L1-PDGFRA (PubMed=23637631).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Leu57Trp (c.170T>G); ClinVar=VCV000185713; Zygosity=Unspecified (PubMed=22675565).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 2Y
Category Cancer cell line

PubMed=2786436; DOI=10.1182/blood.V73.8.2182.2182
Smith S.D., McFall P., Morgan R., Link M.P., Hecht F., Cleary M.L., Sklar J.
Long-term growth of malignant thymocytes in vitro.
Blood 73:2182-2187(1989)

PubMed=1720549; DOI=10.1073/pnas.88.23.10735
Ziemin-van der Poel S., McCabe N.R., Gill H.J., Espinosa R. III, Patel Y., Harden A., Rubinelli P., Smith S.D., Le Beau M.M., Rowley J.D., Diaz M.O.
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
Proc. Natl. Acad. Sci. U.S.A. 88:10735-10739(1991)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=15472075; DOI=10.1126/science.1102160
Weng A.P., Ferrando A.A., Lee W., Morris J.P. IV, Silverman L.B., Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C.
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Science 306:269-271(2004)

PubMed=22675565; DOI=10.1371/journal.pone.0038463
Atak Z.K., De Keersmaecker K., Gianfelici V., Geerdens E., Vandepoel R., Pauwels D., Porcu M., Lahortiga I., Brys V., Dirks W.G., Quentmeier H., Cloos J., Cuppens H., Uyttebroeck A., Vandenberghe P., Cools J., Aerts S.
High accuracy mutation detection in leukemia on a selected panel of cancer genes.
PLoS ONE 7:E38463-E38463(2012)

PubMed=23637631; DOI=10.1371/journal.pgen.1003464
Giacomini C.P., Sun S., Varma S., Shain A.H., Giacomini M.M., Balagtas J.M.S., Sweeney R.T., Lai E., Del Vecchio C.A., Forster A.D., Clarke N., Montgomery K.D., Zhu S., Wong A.J., van de Rijn M., West R.B., Pollack J.R.
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
PLoS Genet. 9:E1003464-E1003464(2013)

Encyclopedic resources Wikidata; Q54970894
Polymorphism and mutation databases Cosmic; 913417
Cosmic; 1115600
Cosmic; 1151793
Cosmic; 1760533
Cosmic; 2165709
Entry history
Entry creation06-Jun-2012
Last entry update21-Mar-2023
Version number21