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Cellosaurus UCLA 2 (CVCL_9953)

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Cell line name UCLA 2
Synonyms UCLA2
Accession CVCL_9953
Resource Identification Initiative To cite this cell line use: UCLA 2 (RRID:CVCL_9953)
Comments From: University of California, Los Angeles; Los Angeles; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0059.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_F1HB (UCLA 2-AGDT)CVCL_F1HC (UCLA 2-AGZT)CVCL_F1HD (UCLA 2-STAG)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=22058289; DOI=10.1093/hmg/ddr506; PMCID=PMC3263987
Silvia V. Diaz Perez, Rachel Kim, Zi-Wei Li, Victor E. Marquez, Sanjeet Patel, Kathrin Plath, Amander Therese Clark;
Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin.
Hum. Mol. Genet. 21:751-764(2012)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0059
Encyclopedic resources Wikidata; Q54989649
Gene expression databases GEO; GSM1395312
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number16