Cellosaurus cell line WIBR2 (CVCL

Cellosaurus WIBR2 (CVCL_9766)

Cross-references
Cell line name	WIBR2
Synonyms	WIBR 2; WIBRe002-A
Accession	CVCL_9766
Resource Identification Initiative	To cite this cell line use: WIBR2 (RRID:CVCL_9766)
Comments	From: Whitehead Institute for Biomedical Research; Boston; USA. Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0075. Registration: Swiss research registry; BAG-hES-IMP-0094. Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-58. Omics: Genomics; ChIP-seq; H3K27me3. Omics: Genomics; ChIP-seq; H3K4me3. Omics: Genomics; Whole exome sequencing. Omics: Transcriptomics; Microarray. Omics: Variations; SNP array analysis. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=20471072; DOI=10.1016/j.cell.2010.04.010 Christopher J. Lengner, Alexander A. Gimelbrant, Jennifer Ann Erwin, Albert Wu Cheng, Matthew G. Guenther, G. Grant Welstead, Raaji Alagappan, Garrett M. Frampton, Ping Xu, Julien Muffat, Sandro Santagata ...Show all 17 authors... , Doug Powers, C. Brent Barrett, Richard Allen Young, Jeannie T. Lee, Rudolf Jaenisch, Maya Mitalipova; Show fewer authors Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141:872-883(2010) PubMed=25090446; DOI=10.1016/j.stem.2014.07.002; PMCID=PMC4184977 Thorold W. Theunissen, Benjamin E. Powell, Hao-Yi Wang, Maya Mitalipova, Dina A. Faddah, Jessica Reddy, Zi-Peng Fan, Dorothea Maetzel, Kibibi Ganz, Lin-Yu Shi, Tenzin Lungjangwa ...Show all 21 authors... , Sumeth Imsoonthornruksa, Yonatan Stelzer, Sudharshan Rangarajan, Ana C. D'Alessio, Jian-Ming Zhang, Qing Gao, Meelad M. Dawlaty, Richard Allen Young, Nathanael S. Gray, Rudolf Jaenisch; Show fewer authors Systematic identification of culture conditions for induction and maintenance of naive human pluripotency. Cell Stem Cell 15:471-487(2014) PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175 Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations. Nature 545:229-233(2017)
Cell line databases/resources	hPSCreg; WIBRe002-A NIHhESC; NIHhESC-10-0075 SKIP; SKIP002898
Biological sample resources	BioSamples; SAMEA2660497
Encyclopedic resources	Wikidata; Q54994040
Gene expression databases	GEO; GSM523598 GEO; GSM523599 GEO; GSM529409 GEO; GSM529412 GEO; GSM529415 GEO; GSM529418
Entry history
Entry creation	06-Jun-2012
Last entry update	14-Aug-2025
Version number	18