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Cellosaurus WIBR2 (CVCL_9766)

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Cell line name WIBR2
Synonyms WIBR 2; WIBRe002-A
Accession CVCL_9766
Resource Identification Initiative To cite this cell line use: WIBR2 (RRID:CVCL_9766)
Comments From: Whitehead Institute for Biomedical Research; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0075.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-58.
Omics: Deep exome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell

PubMed=20471072; DOI=10.1016/j.cell.2010.04.010
Lengner C.J., Gimelbrant A.A., Erwin J.A., Cheng A.W., Guenther M.G., Welstead G.G., Alagappan R., Frampton G.M., Xu P., Muffat J., Santagata S., Powers D., Barrett C.B., Young R.A., Lee J.T., Jaenisch R., Mitalipova M.
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.
Cell 141:872-883(2010)

PubMed=25090446; DOI=10.1016/j.stem.2014.07.002
Theunissen T.W., Powell B.E., Wang H.-Y., Mitalipova M., Faddah D.A., Reddy J., Fan Z.-P., Maetzel D., Ganz K., Shi L.-Y., Lungjangwa T., Imsoonthornruksa S., Stelzer Y., Rangarajan S., D'Alessio A.C., Zhang J.-M., Gao Q., Dawlaty M.M., Young R.A., Gray N.S., Jaenisch R.
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency.
Cell Stem Cell 15:471-487(2014)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cell line databases/resources hPSCreg; WIBRe002-A
ISCR; 1425
NIHhESC; NIHhESC-10-0075
SKIP; SKIP002898
Biological sample resources BioSamples; SAMEA2660497
Encyclopedic resources Wikidata; Q54994040
Gene expression databases GEO; GSM523598
GEO; GSM523599
GEO; GSM529409
GEO; GSM529412
GEO; GSM529415
GEO; GSM529418
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number15