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Cellosaurus STA-ET-8.1 (CVCL_9695)

[Text version]
Cell line name STA-ET-8.1
Synonyms STA-ET-8; St. Anna Kinderspital-Ewing Tumor-8.1
Accession CVCL_9695
Resource Identification Initiative To cite this cell line use: STA-ET-8.1 (RRID:CVCL_9695)
Comments From: Children's Cancer Research Institute; Vienna; Austria.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Thr (c.454C>A); Zygosity=Unspecified (PubMed=25223734).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9696 ! STA-ET-8.2
Category Cancer cell line
Publications

PubMed=8378080
Heinrich Kovar, Andreas Auinger, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Mechthild Salzer-Kuntschik, Helmut Gadner;
Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.
Oncogene 8:2683-2690(1993)

PubMed=9393981; DOI=10.1038/sj.onc.1201397
Heinrich Kovar, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Peter F. Ambros, Bernadette Gruber, Reinhard Windhager, Helmut Gadner;
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Oncogene 15:2225-2232(1997)

PubMed=25223734; DOI=10.1158/2159-8290.CD-14-0622; PMCID=PMC4264969
Franck Tirode, Didier Surdez, Xiao-Tu Ma, Matthew Parker, Marie-Cecile Le Deley, Armita Bahrami, Zhao-Jie Zhang, Eve Lapouble, Sandrine Grossetete-Lalami, Michael Rusch, Stephanie Reynaud ...Show all 35 authors... , Thomas Rio-Frio, Erin Hedlund, Gang Wu, Xiang Chen, Gaelle Pierron, Odile Oberlin, Sakina Zaidi, Gordon Lemmon, Pankaj Gupta, Bhavin Vadodaria, John Easton, Marta Gut, Li Ding, Elaine R. Mardis, Richard K. Wilson, Sheila Shurtleff, Valerie Laurence, Jean Michon, Perrine Marec-Berard, Ivo G. Gut, James R. Downing, Michael Anthony Dyer, Jing-Hui Zhang, Olivier Delattre; Show fewer authors
International Cancer Genome Consortium
St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project
Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.
Cancer Discov. 4:1342-1353(2014)

Cross-references
Encyclopedic resources Wikidata; Q54955781
Polymorphism and mutation databases Cosmic; 2250478
IARC_TP53; 23649
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number13