Cellosaurus cell line STA-ET-7.2 (CVCL

Cellosaurus STA-ET-7.2 (CVCL_9693)

Cross-references
Cell line name	STA-ET-7.2
Synonyms	STA-ET-7_2; St. Anna Kinderspital-Ewing Tumor-7.2
Accession	CVCL_9693
Resource Identification Initiative	To cite this cell line use: STA-ET-7.2 (RRID:CVCL_9693)
Comments	From: Children's Cancer Research Institute; Vienna; Austria. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8378080).
Disease	Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_9692 ! STA-ET-7.1 CVCL_9694 ! STA-ET-7.3
Category	Cancer cell line
Publications	PubMed=8378080 Heinrich Kovar, Andreas Auinger, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Mechthild Salzer-Kuntschik, Helmut Gadner; Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours. Oncogene 8:2683-2690(1993) PubMed=9393981; DOI=10.1038/sj.onc.1201397 Heinrich Kovar, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Peter F. Ambros, Bernadette Gruber, Reinhard Windhager, Helmut Gadner; Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene 15:2225-2232(1997) PubMed=11507040 Heinrich Kovar, Gunhild Jug, Claudia Maria Hattinger, Laura Spahn, Dave N.T. Aryee, Peter F. Ambros, Andreas Zoubek, Helmut Gadner; The EWS protein is dispensable for Ewing tumor growth. Cancer Res. 61:5992-5997(2001)
Cell line databases/resources	cancercelllines; CVCL_9693
Encyclopedic resources	Wikidata; Q54955778
Polymorphism and mutation databases	Cosmic; 1388899 IARC_TP53; 23648
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	13