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Cellosaurus BL41-K3 (CVCL_9667)

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Cell line name BL41-K3
Synonyms BL41/K3; BL41 K3; BL41K3
Accession CVCL_9667
Resource Identification Initiative To cite this cell line use: BL41-K3 (RRID:CVCL_9667)
Comments Population: Caucasian.
Virology: EBV-negative.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P12978; Epstein-Barr virus (strain B95-8) EBNA2.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1087 (BL-41)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=8553575; DOI=10.1006/viro.1995.0084
Bettina Kempkes, Michael Pawlita, Ursula Zimber-Strobl, Gunther Eissner, Gerhard Laux, Georg-Wilhelm Bornkamm;
Epstein-Barr virus nuclear antigen 2-estrogen receptor fusion proteins transactivate viral and cellular genes and interact with RBP-J kappa in a conditional fashion.
Virology 214:675-679(1995)

PubMed=8627226; DOI=10.1099/0022-1317-77-2-227
Bettina Kempkes, Ursula Zimber-Strobl, Gunther Eissner, Michael Pawlita, Martin H. Falk, Wolfgang Hammerschmidt, Georg-Wilhelm Bornkamm;
Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines.
J. Gen. Virol. 77:227-237(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9667
Encyclopedic resources Wikidata; Q54797314
Experimental variables resources EFO; EFO_0001091
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18