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Cellosaurus T-47Daro (CVCL_9582)

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Cell line name T-47Daro
Accession CVCL_9582
Resource Identification Initiative To cite this cell line use: T-47Daro (RRID:CVCL_9582)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2594; CYP19A1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=9449203; DOI=10.1016/S0960-0760(97)00068-X
Xiu-Zhu Sun, Du-Jin Zhou, Shiu-An Chen;
Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells.
J. Steroid Biochem. Mol. Biol. 63:29-36(1997)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9582
Encyclopedic resources Wikidata; Q54971348
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number21