Cellosaurus logo
expasy logo

Cellosaurus SLK (CVCL_9569)

[Text][XML][JSON]
Cell line name SLK
Synonyms KS-SLK
Accession CVCL_9569
Resource Identification Initiative To cite this cell line use: SLK (RRID:CVCL_9569)
Comments Problematic cell line: Contaminated. Shown to be a Caki-1 derivative (PubMed=22987579). Originally thought to originate from a 28 year old male patient with HIV-1 negative Kaposi sarcoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00477.
Population: Caucasian.
Doubling time: 24-36 hours (PubMed=7520247).
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Leu98Pro (c.293T>C); ClinVar=VCV001502192; Zygosity=Heterozygous (from parent cell line).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0234 (Caki-1)
Children:
CVCL_B6YU (iSLK)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): PubMed=22987579

Markers:
AmelogeninX
CSF1PO10,11
D5S81811,12
D7S8208,12
D13S31711,12
D16S53912
TH016,8
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=7520247; DOI=10.1097/00002030-199405000-00002
Brian Garnet Herndier, Albrecht Werner, Paul Arnstein, Nancy W. Abbey, Francesco Demartis, Robert L. Cohen, Marc A. Shuman, Jay A. Levy;
Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals.
AIDS 8:575-581(1994)

DOI=10.1007/0-306-46861-1_10
Chris Boshoff;
Kaposi's sarcoma.
(In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.157-166; Kluwer Academic Publishers; New York; USA (1999)

PubMed=22987579; DOI=10.1002/ijc.27849
Michael Sturzl, Dominika Gaus, Wilhelm Gerhard Dirks, Donald Emil Ganem, Ramona Jochmann;
Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line.
Int. J. Cancer 132:1954-1958(2013)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-9402
Cell line databases/resources SKY/M-FISH/CGH; 3862
Biological sample resources BioSample; SAMN03151616
Encyclopedic resources Wikidata; Q54954867
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number27