Cellosaurus cell line Karpas-1272 (CVCL

Cellosaurus Karpas-1272 (CVCL_9554)

Cross-references
Cell line name	Karpas-1272
Synonyms	Karpas 1272; Karpas1272
Accession	CVCL_9554
Resource Identification Initiative	To cite this cell line use: Karpas-1272 (RRID:CVCL_9554)
Comments	Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: Plasma cell; CL=CL_0000786.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Unspecified (PubMed=11157491).
Disease	Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	36Y
Category	Cancer cell line
Web pages	Provider; Cambridge Enterprise; -; https://www.enterprise.cam.ac.uk/reagents/karpas-1272-human-myeloma-cell-line/
Publications	PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2 Hans Gunther Drexler, Yoshinobu Matsuo; Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia. Leuk. Res. 24:681-703(2000) PubMed=11157491; DOI=10.1182/blood.V97.3.729 Marta Chesi, Leslie A. Brents, Sarah A. Ely, Carlos Bais, Davide F. Robbiani, Enrique A. Mesri, Walter Michael Kuehl, Peter Leif Bergsagel; Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma. Blood 97:729-736(2001) PubMed=15621787; DOI=10.1080/10428190400002244 Abraham Karpas, Lana Harder, Barbara H. Czepulkowski, David Bloxham, Rani Saward, Alla Dremucheva, Reiner Siebert; Studies of four new human myeloma cell lines. Leuk. Lymphoma 46:101-112(2005)
Cell line databases/resources	cancercelllines; CVCL_9554
Encyclopedic resources	Wikidata; Q54899483
Polymorphism and mutation databases	Cosmic; 720772
Entry history
Entry creation	06-Jun-2012
Last entry update	14-Aug-2025
Version number	18