Cellosaurus cell line KHM-4 (CVCL

Cellosaurus KHM-4 (CVCL_9545)

Cross-references
Cell line name	KHM-4
Synonyms	KHM4
Accession	CVCL_9545
Resource Identification Initiative	To cite this cell line use: KHM-4 (RRID:CVCL_9545)
Comments	Population: Japanese. Characteristics: Produces IgA kappa. Omics: Variations; Array-based CGH. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. Cell type: Plasma cell; CL=CL_0000786.
Disease	Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	51Y
Category	Cancer cell line
Publications	PubMed=1611184; DOI=10.2169/internalmedicine.31.339 Hiromitsu Matsuzaki, Fumihiko Matsuno, Minoru Yoshida, Hiroyuki Hata, Koushiro Okazaki, Kiyoshi Takatsuki; Human myeloma cell line (KHM-4) established from a patient with multiple myeloma associated with hyperammonemia. Intern. Med. 31:339-343(1992) PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2 Hans Gunther Drexler, Yoshinobu Matsuo; Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia. Leuk. Res. 24:681-703(2000) PubMed=15215163; DOI=10.1016/S0002-9440(10)63276-2; PMCID=PMC1618545 Jun Inoue, Takemi Otsuki, Akira Hirasawa, Issei Imoto, Yoshinobu Matsuo, Shiroh Shimizu, Masafumi Taniwaki, Johji Inazawa; Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma. Am. J. Pathol. 165:71-81(2004)
Cell line databases/resources	CGH-DB; 9160-4
Encyclopedic resources	Wikidata; Q54899905
Entry history
Entry creation	06-Jun-2012
Last entry update	14-Aug-2025
Version number	17