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Cellosaurus SMS-LHN (CVCL_9539)

[Text version]
Cell line name SMS-LHN
Accession CVCL_9539
Resource Identification Initiative To cite this cell line use: SMS-LHN (RRID:CVCL_9539)
Comments Characteristics: Neuroblastic type (N-type) (PubMed=15720811).
Doubling time: 216 hours (COG).
Omics: Variations; Array-based CGH.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,19
D3S135816,18
D5S81810,11
D7S8208,11
D8S117913,14
D13S3179,13
D16S5398,9
D18S5116,19
D19S43315
D21S1127,28
FGA19,23
TH019.3,10
TPOX8,9
vWA15,18

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Web pages Provider; CCR; -; https://www.cccells.org/dl/NB_Data_Sheets/SMS-LHN_Cell_Line_Data_Sheet_COGcell_org.pdf
Publications

PubMed=7037175
Charles Patrick Reynolds, Debra A. Reynolds, Eugene Philip Frenkel, R. Graham Smith;
Selective toxicity of 6-hydroxydopamine and ascorbate for human neuroblastoma in vitro: a model for clearing marrow prior to autologous transplant.
Cancer Res. 42:1331-1336(1982)

PubMed=8242562; DOI=10.1002/1097-0142(19931201)72:11<3346::AID-CNCR2820721134>3.0.CO;2-E
Randal K. Wada, Robert C. Seeger, Garrett M. Brodeur, Peggy A. Einhorn, Sylvia A. Rayner, Mary M. Tomayko, Charles Patrick Reynolds;
Human neuroblastoma cell lines that express N-myc without gene amplification.
Cancer 72:3346-3354(1993)

DOI=10.1007/0-306-46872-7_2
Carol Jeanne Thiele;
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=11507071
Nino Keshelava, Juan J. Zuo, Ping Chen, Sitara N. Waidyaratne, Marian C. Luna, Charles Joseph Gomer, Timothy J. Triche, Charles Patrick Reynolds;
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001)

PubMed=15720811; DOI=10.1593/neo.04310; PMCID=PMC1531688
Jeanette D. Walton, David R. Kattan, Sharon K. Thomas, Barbara A. Spengler, Hong-Fen Guo, June Lee Biedler, Nai-Kong V. Cheung, Robert A. Ross;
Characteristics of stem cells from human neuroblastoma cell lines and in tumors.
Neoplasia 6:838-845(2004)

PubMed=15892104; DOI=10.1002/gcc.20198
Yael P. Mosse, Joel Greshock, Adam A. Margolin, Tara Naylor, Kristina A. Cole, Deepa Khazi, George Hii, Cynthia Winter, Syed Shahzad, Muhammad Usman Asziz, Jaclyn A. Biegel ...Show all 13 authors... , Barbara L. Weber, John Matthew Maris; Show fewer authors
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Ahsan S. Farooqi, Rebecca A. Dagg, L. Mi Rim Choi, Jerry W. Shay, Charles Patrick Reynolds, Loretta M.S. Lau;
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54954993
Polymorphism and mutation databases Cosmic; 717429
Cosmic; 848931
IARC_TP53; 23821
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number16