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Cellosaurus HeLa-APL (CVCL_9493)

[Text version]
Cell line name HeLa-APL
Synonyms HeLa-R
Accession CVCL_9493
Resource Identification Initiative To cite this cell line use: HeLa-APL (RRID:CVCL_9493)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:90205; Plitidepsin (Dehydrodidemnin B; Aplidin).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Proteome analysis by 2D-DE/MS.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=15365569; DOI=10.1038/sj.bjc.6602166
Losada A., Lopez-Oliva J.M., Sanchez-Puelles J.M., Garcia-Fernandez L.F.
Establishment and characterisation of a human carcinoma cell line with acquired resistance to aplidin.
Br. J. Cancer 91:1405-1413(2004)

PubMed=17338558; DOI=10.1021/pr060430+
Gonzalez-Santiago L., Alfonso P., Suarez Y., Nunez A., Garcia-Fernandez L.F., Alvarez E., Munoz A., Casal J.I.
Proteomic analysis of the resistance to aplidin in human cancer cells.
J. Proteome Res. 6:1286-1294(2007)

Cross-references
Encyclopedic resources Wikidata; Q54882709
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number16