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Cellosaurus MUG-Chor1 (CVCL_9277)

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Cell line name MUG-Chor1
Synonyms MUG-CHOR1; MUGCHOR1; Medical University of Graz-Chordoma 1
Accession CVCL_9277
Resource Identification Initiative To cite this cell line use: MUG-Chor1 (RRID:CVCL_9277)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~75-100 hours (DSMZ=ACC-755); 5 days (Chordoma Foundation).
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Derived from site: In situ; Bone, sacrum; UBERON=UBERON_0003690.
Sequence variations
HLA typing Source: Chordoma Foundation
Class I
HLA-AA*11
Disease Sacral chordoma (NCIt: C129927)
Chordoma (ORDO: Orphanet_178)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3219; DSMZ=ACC-755; PubMed=22002331; PubMed=27102572; PubMed=28835717

Markers:
AmelogeninX
CSF1PO11
D2S133818,20
D3S135814,17
D5S81811,12
D7S8208,11
D8S117911,12
D13S31711
D16S53911,14
D18S5117,22.2 (DSMZ=ACC-755)
17,23 (PubMed=22002331; PubMed=27102572; PubMed=28835717)
D19S43313,14
D21S1129,33.2
FGA21,26
Penta D13
Penta E5,12
TH019.3
TPOX8
vWA15

Run an STR similarity search on this cell line
Web pages Info; Chordoma Foundation; -; https://www.chordomafoundation.org/researchers/disease-models/mug-chor1/
Publications

PubMed=22002331; DOI=10.3892/ijo.2011.1235
Beate Rinner, Elke Verena Froehlich, Karin Buerger, Heike Knausz, Birgit Lohberger, Susanne Scheipl, Carina Fischer, Andreas Leithner, Christian Guelly, Slave Trajanoski, Karoly Szuhai, Bernadette Liegl-Atzwanger;
Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1.
Int. J. Oncol. 40:443-451(2012)

PubMed=27102572; DOI=10.1002/path.4729; PMCID=PMC4922416
Susanne Scheipl, Michelle Barnard, Lucia Cottone, Mette Jorgensen, David Harold Drewry, William J. Zuercher, Fabrice Turlais, Hong-Tao Ye, Ana P. Leite, James A. Smith, Andreas Leithner ...Show all 19 authors... , Peter Moller, Silke Bruderlein, Naomi Guppy, Fernanda Amary, Roberto Tirabosco, Sandra J. Strauss, Nischalan Pillay, Adrienne M. Flanagan; Show fewer authors
EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J. Pathol. 239:320-334(2016)

PubMed=28515451; DOI=10.1038/s41598-017-02174-5; PMCID=PMC5435709
Daniela Jager, Thomas F.E. Barth, Silke Bruderlein, Angelika Scheuerle, Beate Rinner, Adrian von Witzleben, Andre Lechel, Patrick Meyer, Regine Mayer-Steinacker, Alexandra von Baer, Markus Schultheiss ...Show all 14 authors... , Christian R. Wirtz, Peter Moller, Kevin Mellert; Show fewer authors
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci. Rep. 7:2032-2032(2017)

PubMed=28835717; DOI=10.1038/s41598-017-10044-3; PMCID=PMC5569021
Roberta Bosotti, Paola Magnaghi, Sebastiano Di Bella, Liviana Cozzi, Carlo Cusi, Fabio Bozzi, Nicola Beltrami, Giovanni Carapezza, Dario Ballinari, Nadia Amboldi, Rosita Lupi ...Show all 18 authors... , Alessio Somaschini, Laura Raddrizzani, Barbara Salom, Arturo Galvani, Silvia Stacchiotti, Elena Tamborini, Antonella Isacchi; Show fewer authors
Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.
Sci. Rep. 7:9226-9226(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3219
DSMZ; ACC-755
Cell line databases/resources cancercelllines; CVCL_9277
Cell_Model_Passport; SIDM01427
DepMap; ACH-001956
DSMZCellDive; ACC-755
Encyclopedic resources Wikidata; Q54907056
Gene expression databases GEO; GSM631722
GEO; GSM631723
Polymorphism and mutation databases Cosmic; 2663861
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number28