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Cellosaurus K562-L (CVCL_9122)

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Cell line name K562-L
Accession CVCL_9122
Resource Identification Initiative To cite this cell line use: K562-L (RRID:CVCL_9122)
Comments Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=7689892; DOI=10.1248/bpb.16.548
Dai Sasaki, Satoshi Kosunago, Junko Hirano, Keiichiroh Matsuda, Yoko Hata, Yoshimitsu Komiyama, Takeshi Mikami, Tatsuji Matsumoto, Masuko Suzuki;
Cloning and characterization of K562 cells on hemoglobin synthetic activity.
Biol. Pharm. Bull. 16:548-551(1993)

Cross-references
Encyclopedic resources Wikidata; Q54899393
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number20