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Cellosaurus K562(S) (CVCL_9119)

[Text version]
Cell line name K562(S)
Synonyms K-562 clone S; K-562, clone S
Accession CVCL_9119
Resource Identification Initiative To cite this cell line use: K562(S) (RRID:CVCL_9119)
Comments Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=6934848
Livia Cioe, Alistair McNab, Howard R. Hubbell, Pacifico Meo, Peter Curtis, Giovanni Rovera;
Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid.
Cancer Res. 41:237-243(1981)

Cross-references
Cell line databases/resources CLO; CLO_0007062
CLDB; cl2986
Encyclopedic resources Wikidata; Q54899421
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number20