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Cellosaurus GENEA021 (CVCL_9030)

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Cell line name GENEA021
Synonyms Genea021; GEN021; SIVF021; SIVF-021; GENEAe021-A
Accession CVCL_9030
Resource Identification Initiative To cite this cell line use: GENEA021 (RRID:CVCL_9030)
Comments From: Genea Biocells, Ltd; Sydney; Australia.
Registration: Swiss research registry; BAG-hES-IMP-0027.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC14-60.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Donor information: Embryo is sibling to those giving rise to GENEA022 (Cellosaurus=CVCL_9031) and GENEA023 (Cellosaurus=CVCL_9032).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=27346003

Markers:
AmelogeninX
CSF1PO11,13
D2S133817,24
D3S135815
D5S81811,12
D7S82011,13
D8S117913,14
D13S31711,12
D16S53911,13
D18S5113,19
D19S43314.2,15
D21S1129,30,32.2
FGA22,24
TH016,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Web pages Provider; Genea; -; https://web.archive.org/web/20180912205435/http://geneabiocells.com/services/shelf-products/human-embryonic-stem-cells/
Publications

PubMed=25645121; DOI=10.1002/stem.1961
Alexis Gina Bosman, Audrey Letourneau, Laura Sartiani, Martina Del Lungo, Flavio Ronzoni, Rostyslav Kuziakiv, Virpi Tohonen, Marco Zucchelli, Federico Andrea Santoni, Michel Guipponi, Biljana Dumevska ...Show all 14 authors... , Outi Hovatta, Stylianos E. Antonarakis, Marisa Elisabetta Elena Jaconi Devaud; Show fewer authors
Perturbations of heart development and function in cardiomyocytes from human embryonic stem cells with trisomy 21.
Stem Cells 33:1434-1446(2015)

PubMed=27346003; DOI=10.1016/j.scr.2016.02.010
Biljana Dumevska, Alexis Gina Bosman, Robert McKernan, Heather Main, Uli Schmidt, Teija Tuulikki Peura;
Derivation of trisomy 21 affected human embryonic stem cell line Genea021.
Stem Cell Res. 16:401-404(2016)

Cross-references
Cell line databases/resources hPSCreg; GENEAe021-A
Biological sample resources BioSamples; SAMEA104130950
Encyclopedic resources Wikidata; Q54835584
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number21