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Cellosaurus GENEA021 (CVCL_9030)

[Text version]
Cell line name GENEA021
Synonyms Genea021; GEN021; SIVF021; SIVF-021; GENEAe021-A
Accession CVCL_9030
Resource Identification Initiative To cite this cell line use: GENEA021 (RRID:CVCL_9030)
Comments From: Genea Biocells, Ltd; Sydney; Australia.
Registration: Swiss research registry; BAG-hES-IMP-0027.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC14-60.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Donor information: Embryo is sibling to those giving rise to GENEA022 (Cellosaurus=CVCL_9031) and GENEA023 (Cellosaurus=CVCL_9032).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=27346003

Markers:
AmelogeninX
CSF1PO11,13
D2S133817,24
D3S135815
D5S81811,12
D7S82011,13
D8S117913,14
D13S31711,12
D16S53911,13
D18S5113,19
D19S43314.2,15
D21S1129,30,32.2
FGA22,24
TH016,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20180912205435/http://geneabiocells.com/services/shelf-products/human-embryonic-stem-cells/
Publications

PubMed=25645121; DOI=10.1002/stem.1961
Bosman A.G., Letourneau A., Sartiani L., Del Lungo M., Ronzoni F., Kuziakiv R., Tohonen V., Zucchelli M., Santoni F.A., Guipponi M., Dumevska B., Hovatta O., Antonarakis S.E., Jaconi Devaud M.E.E.
Perturbations of heart development and function in cardiomyocytes from human embryonic stem cells with trisomy 21.
Stem Cells 33:1434-1446(2015)

PubMed=27346003; DOI=10.1016/j.scr.2016.02.010
Dumevska B., Bosman A.G., McKernan R., Main H., Schmidt U., Peura T.T.
Derivation of trisomy 21 affected human embryonic stem cell line Genea021.
Stem Cell Res. 16:401-404(2016)

Cross-references
Cell line databases/resources hPSCreg; GENEAe021-A
ISCR; 1183
Biological sample resources BioSamples; SAMEA104130950
Encyclopedic resources Wikidata; Q54835584
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number19