Cellosaurus cell line 27e (CVCL

Cellosaurus 27e (CVCL_8998)

Cross-references
Cell line name	27e
Synonyms	iPS-27e; hiPS 27e; hiPS-27e; 27e-ALS; SOD1-27e; HVRDi008-A
Accession	CVCL_8998
Resource Identification Initiative	To cite this cell line use: 27e (RRID:CVCL_8998)
Comments	From: Harvard University; Boston; USA. Omics: Transcriptomics; Microarray. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11179; SOD1; Simple; p.Gly86Ser (c.256G>A) (G85S); ClinVar=VCV000932081; Zygosity=Unspecified (PubMed=21293464).
Disease	Amyotrophic lateral sclerosis 1 (NCIt: C168749) Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_8997 ! 27b
Sex of cell	Female
Age at sampling	29Y
Category	Induced pluripotent stem cell
Publications	PubMed=21293464; DOI=10.1038/nbt.1783; PMCID=PMC3229307 Gabriella L. Boulting, Evangelos Kiskinis, Gist Fralley Croft, Mackenzie Weygandt Mathis, Derek Hayden Oakley, Brian Jason Wainger, Damian J. Williams, David J. Kahler, Mariko Yamaki, Lance S. Davidow, Kit T. Rodolfa ...Show all 18 authors... , John T. Dimos, Shravani Mikkilineni, Amy B. MacDermott, Clifford J. Woolf, Christopher E. Henderson, Hynek Wichterle, Kevin Carl Eggan; Show fewer authors A functionally characterized test set of human induced pluripotent stem cells. Nat. Biotechnol. 29:279-286(2011) PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454 Christoph Bock, Evangelos Kiskinis, Griet Verstappen, Hong-Cang Gu, Gabriella L. Boulting, Zachary D. Smith, Michael Johannes Ziller, Gist Fralley Croft, Mackenzie Weygandt Mathis, Derek Hayden Oakley, Andreas Gnirke ...Show all 13 authors... , Kevin Carl Eggan, Alexander Meissner; Show fewer authors Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144:439-452(2011)
Cell line databases/resources	hPSCreg; HVRDi008-A SKIP; SKIP004432
Biological sample resources	BioSamples; SAMEA13190959 ENCODE; ENCBS626IJF
Encyclopedic resources	Wikidata; Q54583764
Experimental variables resources	EFO; EFO_0007110
Gene expression databases	GEO; GSM637789 GEO; GSM670064
Entry history
Entry creation	06-Jun-2012
Last entry update	10-Apr-2025
Version number	25