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Cellosaurus LNCaP-CR (CVCL_8986)

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Cell line name LNCaP-CR
Accession CVCL_8986
Resource Identification Initiative To cite this cell line use: LNCaP-CR (RRID:CVCL_8986)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0395 (LNCaP)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=16377078; DOI=10.1016/j.canlet.2005.10.040
Manabu Kawada, Hiroyuki Inoue, Ihomi Usami, Kozo Takamoto, Tohru Masuda, Yoko Yamazaki, Daishiro Ikeda;
Establishment of a highly tumorigenic LNCaP cell line having inflammatory cytokine resistance.
Cancer Lett. 242:46-52(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8986
Encyclopedic resources Wikidata; Q54902835
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18