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Cellosaurus R3 (CVCL_8973)

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Cell line name R3
Synonyms 33-10ras3
Accession CVCL_8973
Resource Identification Initiative To cite this cell line use: R3 (RRID:CVCL_8973)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322.
Cell type: Schwann cell; CL=CL_0002573.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Sex of cell Sex unspecified
Age at sampling 2-3D
Category Transformed cell line
Publications

PubMed=3049071; DOI=10.1002/j.1460-2075.1988.tb02990.x; PMCID=PMC457147
Anne Jacqueline Ridley, Hugh F. Paterson, Mark David Noble, Hartmut K. Land;
Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation.
EMBO J. 7:1635-1645(1988)

PubMed=12210843; DOI=10.1002/jnr.10327
Mehreen Hai, Naser Muja, George H. de Vries, Richard Hudson Quarles, Pragna I. Patel;
Comparative analysis of Schwann cell lines as model systems for myelin gene transcription studies.
J. Neurosci. Res. 69:497-508(2002)

Cross-references
Cell line collections (Providers) ATCC; CRL-2764
Cell line databases/resources CLO; CLO_0008713
Encyclopedic resources Wikidata; Q54949038
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number14