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Cellosaurus YD-15 (CVCL_8930)

[Text version]
Cell line name YD-15
Synonyms YD15
Accession CVCL_8930
Resource Identification Initiative To cite this cell line use: YD-15 (RRID:CVCL_8930)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Korean.
Doubling time: 19.8 hours (PubMed=16264262).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.84
Native American1.03
East Asian, North65.12
East Asian, South31.39
South Asian0
European, North0
European, South1.62
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L078 ! YD-15M
Sex of cell Male
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): KCLB=60504; PubMed=16264262

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815
D5S81812
D7S82012,13
D8S117915
D13S31711,12
D16S5399,12
D18S5114
D21S1130,31.2
FGA23
Penta D9
Penta E14,19
TH016,9
TPOX9
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=16264262; DOI=10.1038/emm.2005.48
Eun Ju Lee, Jin Kim, Seoung Ae Lee, Eun-Jung Kim, Yong-Chan Chun, Mi Heon Ryu, Jong-In Yook;
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp. Mol. Med. 37:379-390(2005)

PubMed=21496182; DOI=10.1111/j.1601-0825.2010.01774.x
Kyeong-Hee Choi, Jung-Hyun Shim, Le Diem Huong, Nam-Pyo Cho, Sung-Dae Cho;
Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.
Oral Dis. 17:469-475(2011)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 60504
Cell line databases/resources cancercelllines; CVCL_8930
Cell_Model_Passport; SIDM01411
DepMap; ACH-000836
Biological sample resources BioSample; SAMN10987726
Chemistry resources PharmacoDB; YD15_1681_2019
Encyclopedic resources Wikidata; Q54995383
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887744
GEO; GSM888839
Polymorphism and mutation databases IARC_TP53; 21619
LiGeA; CCLE_509
Progenetix; CVCL_8930
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number31