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Cellosaurus p53NiS1 (CVCL_8902)

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Cell line name p53NiS1
Synonyms P53NiS1
Accession CVCL_8902
Resource Identification Initiative To cite this cell line use: p53NiS1 (RRID:CVCL_8902)
Comments Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53 (Note=1 of 2 alleles).
Transformant: ChEBI; CHEBI_144804; Nickel subsulfide.
Misspelling: P53N1S1; Note=Occasionally.
Derived from site: In situ; Leg; UBERON=UBERON_0000978.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Unexplicit; Deletion in exon 5; Zygosity=Hemizygous (PubMed=11984000).
Disease Mouse sarcoma (NCIt: C21603)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Trp53+/-.
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=11984000; PMCID=PMC2039931
Baskaran Govindarajan, Robert Klafter, Mark Steven Miller, Claire Prouty Mansur, Melissa Mizesko, Xian-He Bai, Kenneth R. LaMontagne Jr., Jack Leonard Arbiser;
Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase.
Mol. Med. 8:1-8(2002)

Cross-references
Cell line collections (Providers) ATCC; CRL-2619
Cell line databases/resources CLO; CLO_0008338
Encyclopedic resources Wikidata; Q54937308
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number10