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Cellosaurus MTC-SK (CVCL_8896)

[Text version]
Cell line name MTC-SK
Synonyms MTC SK
Accession CVCL_8896
Resource Identification Initiative To cite this cell line use: MTC-SK (RRID:CVCL_8896)
Comments Population: Caucasian.
Doubling time: 2.4 days (PubMed=1972348).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Disease Thyroid gland medullary carcinoma (NCIt: C3879)
Medullary thyroid carcinoma (ORDO: Orphanet_1332)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8895 (MTC-F)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=1972348
Roswitha Pfragner, Heinz Hofler, Annemarie Behmel, Elisabeth Ingolic, Veronika Walser;
Establishment and characterization of continuous cell line MTC-SK derived from a human medullary thyroid carcinoma.
Cancer Res. 50:4160-4166(1990)

PubMed=12089864
Roswitha Pfragner, Gerhard Hubert Wirnsberger, Elisabeth Ingolic, Bruno Niederle;
Medullary thyroid carcinomas in cell culture -- models for future therapies.
Wien. Klin. Wochenschr. 114:279-283(2002)

PubMed=15126569; DOI=10.1210/jc.2003-031314
Klaus Kaczirek, Martin Schindl, Andreas Weinhausel, Christian Scheuba, Christian Passler, Gerhard Prager, Markus Raderer, Gerhard Hamilton, Martina Mittlbock, Veronika Siegl, Roswitha Pfragner, Bruno Niederle;
Cytotoxic activity of camptothecin and paclitaxel in newly established continuous human medullary thyroid carcinoma cell lines.
J. Clin. Endocrinol. Metab. 89:2397-2401(2004)

PubMed=17786610; DOI=10.1080/14653240701385836
Guido Stadler, Matthias Wieser, Franz Steindl, Johannes Grillari, Hermann Katinger, Roswitha Pfragner, Regina Voglauer;
Development of standarDIzed cell culture conditions for tumor cells with potential clinical application.
Cytotherapy 9:488-498(2007)

PubMed=22538498; DOI=10.1159/000338793
Simona Grozinsky-Glasberg, Ilan Shimon, Hadara Rubinfeld;
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

CLPUB00412
Zainab Ghazal Siddiqui;
Medullary thyroid cancer: the current state of tumour marker and treatment strategies.
Thesis MD (2015); Medical University of Graz; Graz; Austria

Cross-references
Cell line collections (Providers) ECACC; 92013101 - Discontinued
Cell line databases/resources CLO; CLO_0007896
CLDB; cl3602
Encyclopedic resources Wikidata; Q54906984
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number17