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Cellosaurus HeyA8-MDR (CVCL_8879)

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Cell line name HeyA8-MDR
Synonyms HEYA8MDR
Accession CVCL_8879
Resource Identification Initiative To cite this cell line use: HeyA8-MDR (RRID:CVCL_8879)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Glu (c.1391G>A); ClinVar=VCV000013964; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8878 (HEY A8)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Web pages Provider; MD Anderson CCAC; -; https://www.mdanderson.org/content/dam/mdanderson/documents/core-facilities/Cytogenetics-and-Cell-Authentication-Core/Cell%20Line%20List%203-23-2022.pdf
Publications

PubMed=16951177; DOI=10.1158/0008-5472.CAN-06-1410; PMCID=PMC3202609
Liz Y. Han, Charles N. Landen, Jose G. Trevino, Jyotsnabaran Halder, Yvonne G. Lin, Aparna A. Kamat, Tae-Jin Kim, William M. Merritt, Robert L. Coleman, David M. Gershenson, William C. Shakespeare ...Show all 18 authors... , Yi-Han Wang, Raji Sundaramoorth, Chester A. Metcalf 3rd, David C. Dalgarno, Tomi K. Sawyer, Gary E. Gallick, Anil K. Sood; Show fewer authors
Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma.
Cancer Res. 66:8633-8639(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8879
Encyclopedic resources Wikidata; Q54883220
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19