| Cell line name |
EU-5 |
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| Synonyms |
916; Line 916; Emory University-5 |
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| Accession |
CVCL_8863 |
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| Resource Identification Initiative |
To cite this cell line use: EU-5 (RRID:CVCL_8863) |
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| Comments |
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. |
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| Disease |
Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
10Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=7630190
Mu-Xiang Zhou, Lu-Bing Gu, Charles David James, J. He, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.
Leukemia 9:1159-1161(1995) PubMed=7888679; DOI=10.1182/blood.V85.6.1608.bloodjournal8561608
Mu-Xiang Zhou, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.
Blood 85:1608-1614(1995) PubMed=9108419; DOI=10.1182/blood.V89.8.2986
Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou;
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia.
Blood 89:2986-2993(1997) PubMed=9823951; DOI=10.1038/sj.leu.2401198
Mu-Xiang Zhou, Lu-Bing Gu, Andrew M. Yeager, Harry W. Findley Jr.;
Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.
Leukemia 12:1756-1763(1998) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54832865
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 12 |
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