Cellosaurus cell line EU-4 (CVCL

Cellosaurus EU-4 (CVCL_8862)

Cross-references
Cell line name	EU-4
Synonyms	870; Line 870 Emory University-4
Accession	CVCL_8862
Resource Identification Initiative	To cite this cell line use: EU-4 (RRID:CVCL_8862)
Comments	Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease	Childhood B acute lymphoblastic leukemia (NCIt: C9140) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Children
Category	Cancer cell line
Web pages	Provider; Emory OTT; 12177; https://emoryott.technologypublisher.com/techcase/12177
Publications	PubMed=7630190 Mu-Xiang Zhou, Lu-Bing Gu, Charles David James, Ju He, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.; Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 9:1159-1161(1995) PubMed=7888679; DOI=10.1182/blood.V85.6.1608.bloodjournal8561608 Mu-Xiang Zhou, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.; Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene. Blood 85:1608-1614(1995) PubMed=9108419; DOI=10.1182/blood.V89.8.2986 Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou; Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. Blood 89:2986-2993(1997) PubMed=9823951; DOI=10.1038/sj.leu.2401198 Mu-Xiang Zhou, Lu-Bing Gu, Andrew M. Yeager, Harry W. Findley Jr.; Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia 12:1756-1763(1998)
Encyclopedic resources	Wikidata; Q54832864
Entry history
Entry creation	06-Jun-2012
Last entry update	10-Apr-2025
Version number	14