Cellosaurus cell line EU-13 (CVCL

Cellosaurus EU-13 (CVCL_8859)

Cross-references
Cell line name	EU-13
Synonyms	Emory University-13
Accession	CVCL_8859
Resource Identification Initiative	To cite this cell line use: EU-13 (RRID:CVCL_8859)
Comments	Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=9823951).
Disease	Childhood B acute lymphoblastic leukemia (NCIt: C9140) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Children
Category	Cancer cell line
Publications	PubMed=7630190 Mu-Xiang Zhou, Lu-Bing Gu, Charles David James, Ju He, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.; Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 9:1159-1161(1995) PubMed=9108419; DOI=10.1182/blood.V89.8.2986 Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou; Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. Blood 89:2986-2993(1997) PubMed=9823951; DOI=10.1038/sj.leu.2401198 Mu-Xiang Zhou, Lu-Bing Gu, Andrew M. Yeager, Harry W. Findley Jr.; Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia 12:1756-1763(1998)
Cell line databases/resources	cancercelllines; CVCL_8859
Encyclopedic resources	Wikidata; Q54832861
Polymorphism and mutation databases	IARC_TP53; 10049
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	17