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Cellosaurus SJNB-4 (CVCL_8821)

[Text version]
Cell line name SJNB-4
Synonyms SJNB4; SJNB-4(SD); NB4; NB4-DH
Accession CVCL_8821
Resource Identification Initiative To cite this cell line use: SJNB-4 (RRID:CVCL_8821)
Comments Omics: Array-based CGH.
Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
Publications

PubMed=8516298; DOI=10.1073/pnas.90.12.5539
Johnson M.R., Look A.T., DeClue J.E., Valentine M.B., Lowy D.R.
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999)

PubMed=10935473; DOI=10.1038/sj.neo.7900010
Kong X.-T., Valentine V.A., Rowe S.T., Valentine M.B., Ragsdale S.T., Jones B.G., Wilkinson D.A., Brodeur G.M., Cohn S.L., Look A.T.
Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.
Neoplasia 1:80-89(1999)

PubMed=10933967; DOI=10.1006/mthe.2000.0064
Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R., Harris L.C., Potter P.M., Danks M.K., Guichard S.M.
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Mol. Ther. 1:457-463(2000)

PubMed=15892104; DOI=10.1002/gcc.20198
Mosse Y.P., Greshock J., Margolin A.A., Naylor T., Cole K., Khazi D., Hii G., Winter C., Shahzad S., Asziz M.U., Biegel J.A., Weber B.L., Maris J.M.
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=18923524; DOI=10.1038/nature07399
Chen Y.-Y., Takita J., Choi Y.L., Kato M., Ohira M., Sanada M., Wang L.-L., Soda M., Kikuchi A., Igarashi T., Nakagawara A., Hayashi Y., Mano H., Ogawa S.
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8821
Encyclopedic resources Wikidata; Q54953569
Gene expression databases GEO; GSM314022
GEO; GSM333809
Polymorphism and mutation databases Cosmic; 688079
Cosmic; 801747
Cosmic; 947715
Cosmic; 1037334
Cosmic; 1099131
Cosmic; 1153795
Cosmic; 2131585
IARC_TP53; 15545
Progenetix; CVCL_8821
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number16