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Cellosaurus SJNB-4 (CVCL_8821)

[Text version]
Cell line name SJNB-4
Synonyms SJNB4; SJNB-4(SD); NB4; NB4-DH
Accession CVCL_8821
Resource Identification Initiative To cite this cell line use: SJNB-4 (RRID:CVCL_8821)
Comments Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (IARC_TP53=15545).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
Publications

PubMed=8516298; DOI=10.1073/pnas.90.12.5539; PMCID=PMC46756
Maureen Riordan Johnson, Alfred Thomas Look, Jeffrey E. DeClue, Marcus B. Valentine, Douglas Ronald Lowy;
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993)

DOI=10.1007/0-306-46872-7_2
Carol Jeanne Thiele;
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=10935473; DOI=10.1038/sj.neo.7900010; PMCID=PMC1716055
Xiao-Tang Kong, Virginia A. Valentine, Susan T. Rowe, Marcus B. Valentine, Susan T. Ragsdale, Bart G. Jones, Deborah A. Wilkinson, Garrett M. Brodeur, Susan Lerner Cohn, Alfred Thomas Look;
Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.
Neoplasia 1:80-89(1999)

PubMed=10933967; DOI=10.1006/mthe.2000.0064
Cynthia A. Pawlik, Rekha V. Iyengar, Erik J. Krull, Stephen E. Mason, Ruchi Khanna, Linda C. Harris, Philip M. Potter, Mary K. Danks, Sylvie M. Guichard;
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Mol. Ther. 1:457-463(2000)

PubMed=15892104; DOI=10.1002/gcc.20198
Yael P. Mosse, Joel Greshock, Adam A. Margolin, Tara Naylor, Kristina A. Cole, Deepa Khazi, George Hii, Cynthia Winter, Syed Shahzad, Muhammad Usman Asziz, Jaclyn A. Biegel ...Show all 13 authors... , Barbara L. Weber, John Matthew Maris; Show fewer authors
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=18923524; DOI=10.1038/nature07399
Yu-Yan Chen, Junko Takita, Young Lim Choi, Motohiro Kato, Miki Ohira, Masashi Sanada, Li-Li Wang, Manabu Soda, Akira Kikuchi, Takashi Igarashi, Akira Nakagawara ...Show all 14 authors... , Yasuhide Hayashi, Hiroyuki Mano, Seishi Ogawa; Show fewer authors
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8821
Encyclopedic resources Wikidata; Q54953569
Gene expression databases GEO; GSM314022
GEO; GSM333809
Polymorphism and mutation databases Cosmic; 688079
Cosmic; 801747
Cosmic; 947715
Cosmic; 1037334
Cosmic; 1099131
Cosmic; 1153795
Cosmic; 2131585
IARC_TP53; 15545
Progenetix; CVCL_8821
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19