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Cellosaurus OCI-Ly4 (CVCL_8801)

[Text version]
Cell line name OCI-Ly4
Synonyms OCI-LY4; OCI-LY-4; OCI-Ly 4; Ly4; LY4
Accession CVCL_8801
Resource Identification Initiative To cite this cell line use: OCI-Ly4 (RRID:CVCL_8801)
Comments From: Ontario Cancer Institute (OCI); Toronto; Canada.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Diffuse large B-cell lymphoma (NCIt: C8851)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 21Y
Category Cancer cell line
Publications

PubMed=3567358; DOI=10.1182/blood.V69.5.1307.1307
Mary Elizabeth Tweeddale, Bing Lim, Nazir Jamal, Jean Robinson, John Raymond Zalcberg, Gina Lockwood, Mark David Minden, Hans August Messner;
The presence of clonogenic cells in high-grade malignant lymphoma: a prognostic factor.
Blood 69:1307-1314(1987)

PubMed=8574164; DOI=10.3109/10428199509059672
Hong Chang, John A. Blondal, Sam Benchimol, Mark David Minden, Hans August Messner;
p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.
Leuk. Lymphoma 19:165-171(1995)

PubMed=11807979; DOI=10.1002/gcc.10025
Sukvarsha Mehra, Hans August Messner, Mark David Minden, Raju S.K. Chaganti;
Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines.
Genes Chromosomes Cancer 33:225-234(2002)

PubMed=15126345; DOI=10.1158/0008-5472.CAN-03-3773
Akinobu Ota, Hiroyuki Tagawa, Sivasundaram Karnan, Shinobu Tsuzuki, Abraham Karpas, Shigeki Kira, Yasuko Yoshida, Masao Seto;
Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma.
Cancer Res. 64:3087-3095(2004)

PubMed=19278952; DOI=10.1182/blood-2009-01-202028; PMCID=PMC3401058
Cheng Li, Sang-Woo Kim, Deepak Rai, Aswani R. Bolla, Siddharth Adhvaryu, Marsha C. Kinney, Ryan S. Robetorye, Ricardo C.T. Aguiar;
Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.
Blood 113:6681-6690(2009)

PubMed=20628145; DOI=10.1182/blood-2010-05-282780; PMCID=PMC2995356
Michael Richard Green, Stefano Monti, Scott J. Rodig, Przemyslaw Juszczynski, Treeve Currie, Evan O'Donnell, Bjoern Chapuy, Kunihiko Takeyama, Donna Neuberg, Todd Robert Golub, Jeffery L. Kutok, Margaret Ann Shipp;
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.
Blood 116:3268-3277(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8801
Encyclopedic resources Wikidata; Q54931774
Gene expression databases GEO; GSM380134
GEO; GSM552452
GEO; GSM1035332
GEO; GSM1374788
Polymorphism and mutation databases Cosmic; 1517648
Cosmic; 1541902
Cosmic; 1636684
Cosmic; 2276330
IARC_TP53; 6447
Progenetix; CVCL_8801
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number25