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Cellosaurus OCI-Ly12 (CVCL_8796)

[Text version]
Cell line name OCI-Ly12
Synonyms OCI-LY12; OCI-LY-12; OCI-Ly 12; OCI Ly12; OCILY12; Ly12
Accession CVCL_8796
Resource Identification Initiative To cite this cell line use: OCI-Ly12 (RRID:CVCL_8796)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: Ontario Cancer Institute (OCI); Toronto; Canada.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys238Arg (c.712T>C); ClinVar=VCV000376576; Zygosity=Unspecified (DepMap=ACH-001147).
Disease Grade 1 follicular lymphoma (NCIt: C3465)
Follicular lymphoma (ORDO: Orphanet_545)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=3567358; DOI=10.1182/blood.V69.5.1307.1307
Tweeddale M.E., Lim B., Jamal N., Robinson J., Zalcberg J.R., Lockwood G., Minden M.D., Messner H.A.
The presence of clonogenic cells in high-grade malignant lymphoma: a prognostic factor.
Blood 69:1307-1314(1987)

PubMed=8574164; DOI=10.3109/10428199509059672
Chang H., Blondal J.A., Benchimol S., Minden M.D., Messner H.A.
p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.
Leuk. Lymphoma 19:165-171(1995)

PubMed=10676951; DOI=10.1038/35000501
Alizadeh A.A., Eisen M.B., Davis R.E., Ma C., Lossos I.S., Rosenwald A., Boldrick J.C., Sabet H., Tran T., Yu X., Powell J.I., Yang L.-M., Marti G.E., Moore T., Hudson J. Jr., Lu L.-S., Lewis D.B., Tibshirani R., Sherlock G., Chan W.-C., Greiner T.C., Weisenburger D.D., Armitage J.O., Warnke R.A., Levy R., Wilson W.H., Grever M.R., Byrd J.C., Botstein D., Brown P.O., Staudt L.M.
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
Nature 403:503-511(2000)

PubMed=11807979; DOI=10.1002/gcc.10025
Mehra S., Messner H.A., Minden M.D., Chaganti R.S.K.
Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines.
Genes Chromosomes Cancer 33:225-234(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8796
Cell_Model_Passport; SIDM01882
DepMap; ACH-001147
Encyclopedic resources Wikidata; Q54931762
Gene expression databases GEO; GSM1990
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number20