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Cellosaurus HOC815 (CVCL_8703)

[Text version]
Cell line name HOC815
Synonyms Hoc815; HOC-815
Accession CVCL_8703
Resource Identification Initiative To cite this cell line use: HOC815 (RRID:CVCL_8703)
Comments Population: Japanese.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=1570156
Eiki Sakai, Nobuo Tsuchida;
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=1624295; DOI=10.1002/hed.2880140103
Koichi Rikimaru, Keiko Tadokoro, Tadashi Yamamoto, Shoji Enomoto, Nobuo Tsuchida;
Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck.
Head Neck 14:8-13(1992)

PubMed=17052259; DOI=10.1111/j.1349-7006.2006.00343.x; PMCID=PMC11160012
Ken-ichi Kozaki, Issei Imoto, Atiphan Pimkhaokham, Shogo Hasegawa, Hitoshi Tsuda, Ken Omura, Johji Inazawa;
PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma.
Cancer Sci. 97:1351-1358(2006)

PubMed=17599052; DOI=10.1038/sj.onc.1210589
Emina Suzuki, Issei Imoto, Atiphan Pimkhaokham, Takayuki Nakagawa, Nobuyuki Kamata, Ken-ichi Kozaki, Teruo Amagasa, Johji Inazawa;
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Oncogene 26:7921-7932(2007)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Avaniyapuram Kannan Murugan, Nguyen Thi Hong, Yasuhisa Fukui, Arasambattu Kannan Munirajan, Nobuo Tsuchida;
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)

Cross-references
Cell line databases/resources CGH-DB; 357-2
Encyclopedic resources Wikidata; Q54890120
Polymorphism and mutation databases Cosmic; 930341
Cosmic; 1046031
Cosmic; 1123031
IARC_TP53; 1099
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17