• Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Unspecified (PubMed=18097548).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Glu285Lys (c.853G>A); ClinVar=VCV000420133; Zygosity=Unspecified (PubMed=1570156).
  

PubMed=2654810
Tadokoro K., Ueda M., Ohshima T., Fujita K., Rikimaru K., Takahashi N., Enomoto S., Tsuchida N.
Activation of oncogenes in human oral cancer cells: a novel codon 13 mutation of c-H-ras-1 and concurrent amplifications of c-erbB-1 and c-myc.
Oncogene 4:499-505(1989)

PubMed=1570156
Sakai E., Tsuchida N.
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=10069537; DOI=10.1111/j.1600-0714.1999.tb02006.x
Hoteiya T., Hayashi E., Satomura K., Kamata N., Nagayama M.
Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo.
J. Oral Pathol. Med. 28:107-111(1999)

PubMed=11120485; DOI=10.1016/S1368-8375(00)00059-2
Yokoyama K., Kamata N., Hayashi E., Hoteiya T., Ueda N., Fujimoto R., Nagayama M.
Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.
Oral Oncol. 37:65-71(2001)

PubMed=12632084; DOI=10.3892/ijo.22.4.891
Yokoyama K., Kamata N., Fujimoto R., Tsutsumi S., Tomonari M., Taki M., Hosokawa H., Nagayama M.
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Int. J. Oncol. 22:891-898(2003)

PubMed=17052259; DOI=10.1111/j.1349-7006.2006.00343.x
Kozaki K.-i., Imoto I., Pimkhaokham A., Hasegawa S., Tsuda H., Omura K., Inazawa J.
PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma.
Cancer Sci. 97:1351-1358(2006)

PubMed=17599052; DOI=10.1038/sj.onc.1210589
Suzuki E., Imoto I., Pimkhaokham A., Nakagawa T., Kamata N., Kozaki K.-i., Amagasa T., Inazawa J.
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Oncogene 26:7921-7932(2007)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)