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Cellosaurus Detroit 30A (CVCL_8674)

[Text version]
Cell line name Detroit 30A
Synonyms Detroit-30A; Det-30A; Det30A
Accession CVCL_8674
Resource Identification Initiative To cite this cell line use: Detroit 30A (RRID:CVCL_8674)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=20143388). Originally thought to originate from the ascitic fluid of a 43 year old breast cancer patient.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00041.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

Berman L., Stulberg C.S., Ruddle F.H.
Epithelium-like cells derived from tissue cultures of human bone marrow and ascitic fluid.
J. Mich. State Med. Soc. 55:269-271(1956)

PubMed=13370509; DOI=10.3181/00379727-92-22595
Berman L., Stulberg C.S.
Eight culture strains (Detroit) of human epithelial-like cells.
Proc. Soc. Exp. Biol. Med. 92:730-735(1956)

Berman L., Stulberg C.S., Ruddle F.H.
Human cell culture: morphology of the Detroit strains.
Cancer Res. 17:668-676(1957)

PubMed=5668122; DOI=10.3181/00379727-128-33119
Peterson W.D. Jr., Stulberg C.S., Swanborg N.K., Robinson A.R.
Glucose-6-phosphate dehydrogenase isoenzymes in human cell cultures determined by sucrose-agar gel and cellulose acetate zymograms.
Proc. Soc. Exp. Biol. Med. 128:772-776(1968)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151680
Encyclopedic resources Wikidata; Q54830984
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22