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Cellosaurus 1-1ras1000 (CVCL_8653)

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Cell line name 1-1ras1000
Accession CVCL_8653
Resource Identification Initiative To cite this cell line use: 1-1ras1000 (RRID:CVCL_8653)
Comments Problematic cell line: Misidentified/contaminated. Not from strain BALB/c as originally assigned but from a NIH Swiss strain derivative (PubMed=27844419).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00531.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Swiss albino.
Hierarchy Parent: CVCL_J646 (BALB/3T3 A31-1-1)
Category Transformed cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=8634088; DOI=10.1002/(SICI)1098-2744(199604)15:4<300::AID-MC7>3.0.CO;2-J
Masaaki Tatsuka, Takahide Ota, Nobuyuki Yamagishi, Yasunari Kashihara, Morimasa Wada, Naoki Matsuda, Hiromi Mitsui, Motoharu Seiki, Shizuo Odashima;
Different metastatic potentials of ras- and src-transformed BALB/c 3T3 A31 variant cells.
Mol. Carcinog. 15:300-308(1996)

PubMed=27844419; DOI=10.1007/s11626-016-0104-3; PMCID=PMC5348555
Kozue Uchio-Yamada, Fumio Kasai, Midori Ozawa, Arihiro Kohara;
Incorrect strain information for mouse cell lines: sequential influence of misidentification on sublines.
In Vitro Cell. Dev. Biol. Anim. 53:225-230(2017)

Cross-references
Cell line collections (Providers) JCRB; JCRB1355
Encyclopedic resources Wikidata; Q54423224
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number16