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Cellosaurus MGR3 (CVCL_8565)

[Text version]
Cell line name MGR3
Synonyms MGR 3; UWR3; UWR-3
Accession CVCL_8565
Resource Identification Initiative To cite this cell line use: MGR3 (RRID:CVCL_8565)
Comments Derived from sampling site: Brain.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=18505928).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line

Ali-Osman F., Stein D.E., Renwick A.
Glutathione content and glutathione-S-transferase expression in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human malignant astrocytoma cell lines.
Cancer Res. 50:6976-6980(1990)

Ali-Osman F.
Brain tumors.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999)

PubMed=18505928; DOI=10.1158/1541-7786.MCR-07-2105
Lo H.-W., Stephenson L., Cao X.-Y., Milas M., Pollock R.E., Ali-Osman F.
Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene.
Mol. Cancer Res. 6:843-850(2008)

PubMed=19706761; DOI=10.1158/0008-5472.CAN-09-0886
Lo H.-W., Zhu H., Cao X.-Y., Aldrich A., Ali-Osman F.
A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion.
Cancer Res. 69:6790-6798(2009)

Encyclopedic resources Wikidata; Q54905492
Polymorphism and mutation databases IARC_TP53; 26926
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number13