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Cellosaurus Kasumi-8 (CVCL_8487)

[Text version]
Cell line name Kasumi-8
Synonyms Kasumi8
Accession CVCL_8487
Resource Identification Initiative To cite this cell line use: Kasumi-8 (RRID:CVCL_8487)
Comments Population: Japanese.
Omics: SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=32180206).
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=32180206).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1403

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81810,12
D7S82010,11
D13S3178,9
D16S53910,11
TH019
TPOX8,11
vWA16,18

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Publications

PubMed=32180206; DOI=10.1007/s13577-020-00347-5; PMCID=PMC7324421
Kasai F., Asou H., Ozawa M., Kobayashi K., Kuramitsu H., Satoh M., Kohara A., Kaneko Y., Kawamura M.
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1403
Encyclopedic resources Wikidata; Q54899525
Gene expression databases GEO; GSM4254136
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number18