Cellosaurus cell line Kasumi-10 (CVCL

Cellosaurus Kasumi-10 (CVCL_8485)

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Cell line name

Kasumi-10

Synonyms

KASUMI-10

Accession

CVCL_8485

Resource Identification Initiative

To cite this cell line use: Kasumi-10 (RRID:CVCL_8485)

Comments

Population: Japanese and Korean.
Karyotypic information: While originating from a female patient, it has a XXY karyotype that could be explained by a disorder of sexual development (PubMed=32180206).
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Miscellaneous: STR profile from personal communication of Leo, Isabelle Rose.

Sequence variations

Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7134; MLLT1; Name(s)=KMT2A-MLLT1, MLL-MLLT1, MLL-ENL (PubMed=32180206; PubMed=35354797).
Mutation; HGNC; HGNC:3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (PubMed=32180206).

Disease

Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt: C80342)
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO: Orphanet_585918)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

Category

Cancer cell line

STR profile

Source(s): JCRB=JCRB1410; Direct_author_submission

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D1S1656	15,17
D2S441	11,11.3
D2S1338	19,24
D3S1358	15,16
D5S818	10,12
D7S820	8,10
D8S1179	13,14
D10S1248	12,15
D12S391	18,22
D13S317	8,11
D16S539	9,10
D18S51	13
D19S433	15.2,16
D21S11	30
D22S1045	15,17
DYS391	9
FGA	22,27.2
SE33	20,26.2
TH01	6,9
TPOX	11,12
vWA	17,19

Publications

PubMed=32180206; DOI=10.1007/s13577-020-00347-5; PMCID=PMC7324421
Fumio Kasai, Hiroya Asou, Midori Ozawa, Kazuhiko Kobayashi, Hiroyuki Kuramitsu, Motonobu Satoh, Arihiro Kohara, Yasuhiko Kaneko, Machiko Kawamura;
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900
Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Paivi Ostling ...Show all 17 authors... , Olli-Pekka Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtio, Mattias Vesterlund, Rozbeh Jafari; Show fewer authors
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1410

Encyclopedic resources

Wikidata; Q54899515

Gene expression databases

GEO; GSM4254138
GEO; GSM5137757

Proteomic databases

PRIDE; PXD023662

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number