Cellosaurus cell line Mel20-06-045 (CVCL

Cellosaurus Mel20-06-045 (CVCL_8474)

Cross-references
Cell line name	Mel20-06-045
Synonyms	MEL20-06-045
Accession	CVCL_8474
Resource Identification Initiative	To cite this cell line use: Mel20-06-045 (RRID:CVCL_8474)
Comments	Omics: Transcriptomics; Microarray.
Sequence variations	Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.Gln209Pro (c.626A>C); ClinVar=VCV000375957; Zygosity=Heterozygous (PubMed=21386926).
Disease	Uveal melanoma (NCIt: C7712) Uveal melanoma (ORDO: Orphanet_39044)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=21386926; PMCID=PMC3049736 Barry L. Burgess, Nagesh P. Rao, Ascia Eskin, Stanley F. Nelson, Tara A. McCannel; Characterization of three cell lines derived from fine needle biopsy of choroidal melanoma with metastatic outcome. Mol. Vis. 17:607-615(2011) PubMed=22515704; DOI=10.1186/1476-4598-11-22; PMCID=PMC3444881 Erika Maria von Euw, Mohammad Atefi, Narsis Attar, Connie Chu, Sybil Zachariah, Barry L. Burgess, Stephen Mok, Charles Ng, Deborah J.L. Wong, Bartosz Chmielowski, David I. Lichter ...Show all 15 authors... , Richard C. Koya, Tara A. McCannel, Elena Izmailova, Antoni Ribas; Show fewer authors Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines. Mol. Cancer 11:22.1-22.9(2012)
Cell line databases/resources	cancercelllines; CVCL_8474
Encyclopedic resources	Wikidata; Q54905157
Polymorphism and mutation databases	Cosmic; 1665024
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	16