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Cellosaurus HPC-36M (CVCL_8446)

[Text version]
Cell line name HPC-36M
Synonyms HPC36M
Accession CVCL_8446
Resource Identification Initiative To cite this cell line use: HPC-36M (RRID:CVCL_8446)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a prostate carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00213.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Caution: Was reported to derive from HPC-36 (Cellosaurus=CVCL_M169).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D8S117912,13
D18S5116
D21S1127,28
FGA18,21
TH017
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=8612713; DOI=10.1006/excr.1996.0146
Elizabeth S. Woo, Yukihiro Kondo, Simon C. Watkins, Dale G. Hoyt, John Stephen Lazo;
Nucleophilic distribution of metallothionein in human tumor cells.
Exp. Cell Res. 224:365-371(1996)

PubMed=10754530; DOI=10.1002/(SICI)1097-0045(20000501)43:2<144::AID-PROS9>3.0.CO;2-H
Yasutomo Suzuki, Yukihiro Kondo, Seiichiro Himeno, Kaoru Nemoto, Masao Akimoto, Nobumasa Imura;
Role of antioxidant systems in human androgen-independent prostate cancer cells.
Prostate 43:144-149(2000)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151711
Encyclopedic resources Wikidata; Q54890244
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25