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Cellosaurus HPC-36M (CVCL_8446)

[Text version]
Cell line name HPC-36M
Synonyms HPC36M
Accession CVCL_8446
Resource Identification Initiative To cite this cell line use: HPC-36M (RRID:CVCL_8446)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a prostate carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00213.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Caution: Was reported to derive from HPC-36 (Cellosaurus=CVCL_M169).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D8S117912,13
D18S5116
D21S1127,28
FGA18,21
TH017
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=8612713; DOI=10.1006/excr.1996.0146
Woo E.S., Kondo Y., Watkins S.C., Hoyt D.G., Lazo J.S.
Nucleophilic distribution of metallothionein in human tumor cells.
Exp. Cell Res. 224:365-371(1996)

PubMed=10754530; DOI=10.1002/(SICI)1097-0045(20000501)43:2<144::AID-PROS9>3.0.CO;2-H
Suzuki Y., Kondo Y., Himeno S., Nemoto K., Akimoto M., Imura N.
Role of antioxidant systems in human androgen-independent prostate cancer cells.
Prostate 43:144-149(2000)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151711
Encyclopedic resources Wikidata; Q54890244
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25