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Cellosaurus OU-AML-4 (CVCL_8394)

[Text version]
Cell line name OU-AML-4
Accession CVCL_8394
Resource Identification Initiative To cite this cell line use: OU-AML-4 (RRID:CVCL_8394)
Comments Problematic cell line: Contaminated. Shown to be a OCI-AML-2 derivative (PubMed=12592342; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00250.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 7137; AFDN + HGNC; 7132; KMT2A; Name(s)=KMT2A-AFDN, MLL-MLLT4, MLL-AF6 (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia with t(6;11)(q27;q23) KMT2A-MLLT4 (NCIt: C132105)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1619 (OCI-AML-2)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

PubMed=10027306; DOI=10.1038/sj.bjc.6690064
Zheng A.-P., Castren K., Saily M., Savolainen E.-R., Koistinen P.O., Vahakangas K.H.
p53 status of newly established acute myeloid leukaemia cell lines.
Br. J. Cancer 79:407-415(1999)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151870
Encyclopedic resources Wikidata; Q54936741
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25