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Cellosaurus MUTZ-11 (CVCL_8288)

[Text version]
Cell line name MUTZ-11
Synonyms MUTZ11; Menschliche Und Tierische Zellkulture-11
Accession CVCL_8288
Resource Identification Initiative To cite this cell line use: MUTZ-11 (RRID:CVCL_8288)
Comments Doubling time: 64-98 hours (PubMed=15068904).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (PubMed=12529668).
Disease Acute myelomonocytic leukemia (NCIt: C7463)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

DOI=10.1007/978-3-642-59358-1_22
Hu Z.-B., Quentmeier H., Meyer C., MacLeod R.A.F., Drexler H.G.
Establishment of the two cytokine-dependent acute myeloid leukemia-derived cell lines MUTZ-8 and MUTZ-11.
(In) Acute leukemias IX. Haematology and blood transfusion, Vol. 41; Hiddemann W., Haferlach T., Unterhalt M., Buechner T., Ritter J. (eds.); pp.122-127; Springer; Berlin (2003)

PubMed=12529668; DOI=10.1038/sj.leu.2402740
Quentmeier H., Reinhardt J., Zaborski M., Drexler H.G.
FLT3 mutations in acute myeloid leukemia cell lines.
Leukemia 17:120-124(2003)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=15068904; DOI=10.1016/j.leukres.2003.09.013
Hu Z.-B., Quentmeier H., Meyer C., Kaufmann M., MacLeod R.A.F., Drexler H.G.
New cytokine-dependent acute myeloid leukemia cell line MUTZ-11 with disomic chromosome rearrangement t(16;17).
Leuk. Res. 28:509-515(2004)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

Cross-references
Encyclopedic resources Wikidata; Q54907098
Polymorphism and mutation databases Cosmic; 787415
Cosmic; 975283
Cosmic; 1012103
Cosmic; 1281341
Cosmic; 1465961
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number18