Cellosaurus cell line IHH-A5 (CVCL

Cellosaurus IHH-A5 (CVCL_8278)

Cross-references
Cell line name	IHH-A5
Synonyms	IHH; Immortalized Human Hepatocyte-A5
Accession	CVCL_8278
Resource Identification Initiative	To cite this cell line use: IHH-A5 (RRID:CVCL_8278)
Comments	Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatocyte; CL=CL_0000182.
Sequence variations	Mutation; HGNC; HGNC:8860; PEX7; Unexplicit; Ex1 del; Zygosity=Homozygous (PubMed=28013369).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	59Y
Category	Transformed cell line
Publications	PubMed=9298258; DOI=10.1023/A:1007404028681 Ingrid J. Schippers, Han Moshage, Han Roelofsen, Michael Muller, Hugo S.A. Heymans, Marcel H.J. Ruiters, Folkert Kuipers; Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation. Cell Biol. Toxicol. 13:375-386(1997) PubMed=22594799; DOI=10.3109/13813455.2012.683442 Carolina Huaman Samanez, Sandrine Caron, Olivier Briand, Helene Dehondt, Isabelle Duplan, Folkert Kuipers, Nathalie Hennuyer, Veronique Clavey, Bart Staels; The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism. Arch. Physiol. Biochem. 118:102-111(2012) PubMed=28013369; DOI=10.1007/s00418-016-1532-6; PMCID=PMC5359384 Femke C.C. Klouwer, Janet Koster, Sacha Ferdinandusse, Hans R. Waterham; Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line. Histochem. Cell Biol. 147:537-541(2017)
Cell line databases/resources	Lonza; 8
Anatomy/cell type resources	BTO; BTO_0006147
Encyclopedic resources	Wikidata; Q54897411
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	16