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Cellosaurus SQ-5 (CVCL_8273)

[Text version]
Cell line name SQ-5
Synonyms Sq-5; SQ5
Accession CVCL_8273
Resource Identification Initiative To cite this cell line use: SQ-5 (RRID:CVCL_8273)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a lung carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00269.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=10358721; DOI=10.18926/AMO/31626
Akio Matsushita, Masahiro Tabata, Hiroshi Ueoka, Katsuyuki Kiura, Takuo Shibayama, Keisuke Aoe, Hiroyuki Kohara, Mine Harada;
Establishment of a drug sensitivity panel using human lung cancer cell lines.
Acta Med. Okayama 53:67-75(1999)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Yoshiaki Nagai, Hitoshi Miyazawa, Huqun No_last_name, Tomoaki Tanaka, Kiyoshi Udagawa, Motoyasu Kato, Shunichiro Fukuyama, Akemi Yokote, Kunihiko Kobayashi, Minoru Kanazawa, Koichi Hagiwara;
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x
Kaori Yoshino, Emi Iimura, Kaoru Saijo, Satsuki Iwase, Kiyoko Fukami, Tadao Ohno, Yuichi Obata, Yukio Nakamura;
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum. Cell 19:43-48(2006)

PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846
Raquel Blanco, Reika Iwakawa, Mo-Ying Tang, Takashi Kohno, Barbara Angulo, Ruben Pio, Luis M. Montuenga, John D. Minna, Jun Yokota, Montse Sanchez-Cespedes;
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) RCB; RCB0110 - Discontinued
Biological sample resources BioSample; SAMN03151759
Encyclopedic resources Wikidata; Q54955605
Experimental variables resources EFO; EFO_0002861
Polymorphism and mutation databases Cosmic; 946076
Cosmic; 1219091
Cosmic; 1239914
Cosmic; 1571743
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25