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Cellosaurus Loukes (CVCL_8259)

[Text version]
Cell line name Loukes
Synonyms LOUCKES; Louckes; Loucks
Accession CVCL_8259
Resource Identification Initiative To cite this cell line use: Loukes (RRID:CVCL_8259)
Comments Virology: EBV-negative.
Misspelling: Luckes; NCBI_Iran=C160; PubMed=17254797.
Misspelling: Lukes; PubMed=3026973; PubMed=6231253.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=17254797

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,17
D5S81812
D7S82010
D8S117912
D13S31711,13
D16S53912,13
D18S5115
D21S1129,30
FGA19,20
TH018,10,11
TPOX9
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=6112750; DOI=10.1073/pnas.78.3.1930; PMCID=PMC319249
Vicky L. van Santen, Andrew Cheung, Elliott Dan Kieff;
Epstein-Barr virus RNA VII: size and direction of transcription of virus-specified cytoplasmic RNAs in a transformed cell line.
Proc. Natl. Acad. Sci. U.S.A. 78:1930-1934(1981)

PubMed=6231253; DOI=10.1002/ijc.2910330407
Barbro Ehlin-Henriksson, George Klein;
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Barbro Ehlin-Henriksson, Agneta Manneborg-Sandlund, George Klein;
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=1915267; DOI=10.1002/j.1460-2075.1991.tb07837.x; PMCID=PMC452998
Paul J. Farrell, Gordon J. Allan, Frances Shanahan, Karen Heather Vousden, Tim Crook;
p53 is frequently mutated in Burkitt's lymphoma cell lines.
EMBO J. 10:2879-2887(1991)

PubMed=8896424; DOI=10.1182/blood.V88.9.3562.bloodjournal8893562
Caroline J. Chapman, Jo X. Zhou, Christopher D. Gregory, Alan Bernard Rickinson, Freda K. Stevenson;
VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection.
Blood 88:3562-3568(1996)

PubMed=9192833
Barry W. Cherney, Kishor G. Bhatia, Cecilia Sgadari, Marina I. Gutierrez, Howard S. Mostowski, Sandra E. Pike, Ghanshyam Gupta, Ian Trevor Magrath, Giovanna Tosato;
Role of the p53 tumor suppressor gene in the tumorigenicity of Burkitt's lymphoma cells.
Cancer Res. 57:2508-2515(1997)

PubMed=9973220
Marina I. Gutierrez, Barry W. Cherney, Azhar Hussain, Howard S. Mostowski, Giovanna Tosato, Ian Trevor Magrath, Kishor G. Bhatia;
Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis.
Cancer Res. 59:696-703(1999)

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Shahram Azari, Nahid Ahmadi, Mahmood Jeddi-Tehrani, Fazel Shokri;
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=24590883; DOI=10.1002/gcc.22161
Eva-Maria Murga Penas, Georgia Schilling, Petra Behrmann, Marianne Klokow, Eik Vettorazzi, Carsten Bokemeyer, Judith Dierlamm;
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

Cross-references
Cell line collections (Providers) NCBI_Iran; C160
Cell line databases/resources cancercelllines; CVCL_8259
Encyclopedic resources Wikidata; Q54902893
Polymorphism and mutation databases IARC_TP53; 703
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number26