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Cellosaurus HMV-I (CVCL_8233)

[Text version]
Cell line name HMV-I
Synonyms HMV-1
Accession CVCL_8233
Resource Identification Initiative To cite this cell line use: HMV-I (RRID:CVCL_8233)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from female 65 year old patient with vaginal melanoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00126.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=11416159; TKG

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8208,12
D8S117912
D13S31713.3
D16S5399
D18S5116
D21S1127,28
FGA18,21
TH017
TPOX8,12
vWA16,18,19

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=3361142; DOI=10.1111/1523-1747.ep12560926
Nakamura T., Seki S., Matsubara O., Ito S., Kasuga T.
Specific incorporation of 4-S-cysteinylphenol into human melanoma cells.
J. Invest. Dermatol. 90:725-728(1988)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11416159; DOI=10.1073/pnas.121616198
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=15467732; DOI=10.1038/sj.onc.1208152
Tanami H., Imoto I., Hirasawa A., Yuki Y., Sonoda I., Inoue J., Yasui K., Misawa-Furihata A., Kawakami Y., Inazawa J.
Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.
Oncogene 23:8796-8804(2004)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) RCB; RCB0004 - Discontinued
TKG; TKG 0302
Cell line databases/resources CGH-DB; 9288-4
Biological sample resources BioSample; SAMN03151710
Chemistry resources ChEMBL-Cells; CHEMBL3308666
ChEMBL-Targets; CHEMBL614825
PubChem_Cell_line; CVCL_8233
Encyclopedic resources Wikidata; Q54889974
Polymorphism and mutation databases Cosmic; 874382
Cosmic; 905202
Cosmic; 1007154
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24