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Cellosaurus HMV-I (CVCL_8233)

[Text version]
Cell line name HMV-I
Synonyms HMV-1
Accession CVCL_8233
Resource Identification Initiative To cite this cell line use: HMV-I (RRID:CVCL_8233)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from female 65 year old patient with vaginal melanoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00126.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=11416159; TKG=TKG 0302

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8208,12
D8S117912
D13S31713.3
D16S5399
D18S5116
D21S1127,28
FGA18,21
TH017
TPOX8,12
vWA16,18,19

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=3361142; DOI=10.1111/1523-1747.ep12560926
Takuro Nakamura, Sachiko Seki, Osamu Matsubara, Shosuke Ito, Tsutomu Kasuga;
Specific incorporation of 4-S-cysteinylphenol into human melanoma cells.
J. Invest. Dermatol. 90:725-728(1988)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
Roderick A.F. MacLeod, Wilhelm Gerhard Dirks, Yoshinobu Matsuo, Maren Kaufmann, Herbert Milch, Hans Gunther Drexler;
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=15467732; DOI=10.1038/sj.onc.1208152
Hideaki Tanami, Issei Imoto, Akira Hirasawa, Yasuhiro Yuki, Itaru Sonoda, Jun Inoue, Kohichiroh Yasui, Akiko Misawa-Furihata, Yutaka Kawakami, Johji Inazawa;
Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.
Oncogene 23:8796-8804(2004)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) RCB; RCB0004 - Discontinued
TKG; TKG 0302
Cell line databases/resources CGH-DB; 9288-4
Biological sample resources BioSample; SAMN03151710
Chemistry resources ChEMBL-Cells; CHEMBL3308666
ChEMBL-Targets; CHEMBL614825
PubChem_Cell_line; CVCL_8233
Encyclopedic resources Wikidata; Q54889974
Polymorphism and mutation databases Cosmic; 874382
Cosmic; 905202
Cosmic; 1007154
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26