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Cellosaurus GLC-8 (CVCL_8218)

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Cell line name GLC-8
Synonyms GLC 8; GLC8
Accession CVCL_8218
Resource Identification Initiative To cite this cell line use: GLC-8 (RRID:CVCL_8218)
Comments Doubling time: 34 hours (PubMed=2838297).
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung, bronchus; UBERON=UBERON_0002185.
Sequence variations
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2409557; DOI=10.1073/pnas.82.13.4409; PMCID=PMC391110
Jos L.V. Broers, Desmond Niall Carney, Lou F.M.H. de Leij, Gijsbert Peter Vooijs, Frans C.S. Ramaekers;
Differential expression of intermediate filament proteins distinguishes classic from variant small-cell lung cancer cell lines.
Proc. Natl. Acad. Sci. U.S.A. 82:4409-4413(1985)

PubMed=2838297; DOI=10.1016/0277-5379(88)90311-2
Pieter Edsge Postmus, Lou F.M.H. de Leij, Anneke Y. van der Veen, Geert Mesander, Charles H.C.M. Buys, Job D. Elema;
Two small cell lung cancer cell lines established from rigid bronchoscope biopsies.
Eur. J. Cancer Clin. Oncol. 24:753-763(1988)

PubMed=1320893; DOI=10.1159/000163712
Marken A.E. Verbeeck, Jack P.M. Elands, Lou F.M.H. de Leij, Charles H.C.M. Buys, Desmond Niall Carney, Gerold Bepler, Anton J.M. Roebroek, Wim J.M. van de Ven, J. Peter H. Burbach;
Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines.
Pathobiology 60:136-142(1992)

PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0
Lois M. Mulligan, Tineke Timmer, Stacey M. Ivanchuk, Barbara G. Campling, Leah C. Young, Pamela H. Rabbitts, Vasi Sundaresan, Robert M.W. Hofstra, Charis Eng;
Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinoma.
Genes Chromosomes Cancer 21:326-332(1998)

PubMed=10408787; DOI=10.1097/00019606-199903000-00002
Vanessa M. Hayes, Wim Bleeker, Edwin Verlind, Tineke Timmer, Arend Karrenbeld, John T. Plukker, Munro Peter Marx, Robert M.W. Hofstra, Charles H.C.M. Buys;
Comprehensive TP53-denaturing gradient gel electrophoresis mutation detection assay also applicable to archival paraffin-embedded tissue.
Diagn. Mol. Pathol. 8:2-10(1999)

PubMed=10709110; DOI=10.1002/(SICI)1097-0215(20000315)85:6<871::AID-IJC22>3.0.CO;2-O
Pamela M.J. McLaughlin, Wijnand Helfrich, Klaas Kok, Marcel Mulder, Soesja W. Hu, Marja G.L. Brinker, Marcel H.J. Ruiters, Lou F.M.H. de Leij, Charles H.C.M. Buys;
The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines.
Int. J. Cancer 85:871-876(2000)

PubMed=20631050; DOI=10.1101/gr.106252.110; PMCID=PMC2928498
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C. Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok, Reinhard Ullmann ...Show all 16 authors... , Stefania Purgato, Orazio Palumbo, Massimo Carella, Peter F. Ambros, Mariano Rocchi; Show fewer authors
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Genome Res. 20:1198-1206(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8218
Encyclopedic resources Wikidata; Q54835924
Gene expression databases GEO; GSM554390
GEO; GSM986183
Polymorphism and mutation databases Cosmic; 2239123
IARC_TP53; 11283
Progenetix; CVCL_8218
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number19