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Cellosaurus GLC-3 (CVCL_8212)

[Text version]
Cell line name GLC-3
Synonyms GLC 3; GLC3; OC-Tol; OC-TOL
Accession CVCL_8212
Resource Identification Initiative To cite this cell line use: GLC-3 (RRID:CVCL_8212)
Comments Doubling time: 56 hours (PubMed=2998591).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=2998591
Lou F.M.H. de Leij, Pieter Edsge Postmus, Charles H.C.M. Buys, Job D. Elema, Frans C.S. Ramaekers, Sibrandes Poppema, Marjoleine Brouwer, Anneke Y. van der Veen, Geert Mesander, Tjwan Hauw The;
Characterization of three new variant type cell lines derived from small cell carcinoma of the lung.
Cancer Res. 45:6024-6033(1985)

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Jos L.V. Broers, Mirjam Klein Rot, Tineke Oostendorp, Gerold Bepler, Lou F.M.H. de Leij, Desmond Niall Carney, Gijsbert Peter Vooijs, Frans C.S. Ramaekers;
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=2574988; DOI=10.1038/bjc.1989.376; PMCID=PMC2247271
Peter Buhl Jensen, Lars L. Vindelov, Henrik Roed, Erland Johannes Frederik Demant, Maxwell Sehested, Torben Skovsgaard, Heine Hoi Hansen;
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
Br. J. Cancer 60:838-844(1989)

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Jos L.V. Broers, Eddy P. Mijnheere, Mirjam Klein Rot, Gert Schaart, Alfred Sijlmans, Otto C. Boerman, Frans C.S. Ramaekers;
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991)

PubMed=1314232; DOI=10.1002/ijc.2910510115
Egbert F. Smit, Elisabeth Geertruida Emma de Vries, Hetty Timmer-Bosscha, Lou F.M.H. de Leij, J. Wolter Oosterhuis, Riekeld J. Scheper, Jan J. Weening, Pieter Edsge Postmus, Nanno H. Mulder;
In vitro response of human small-cell lung-cancer cell lines to chemotherapeutic drugs; no correlation with clinical data.
Int. J. Cancer 51:72-78(1992)

PubMed=1320893; DOI=10.1159/000163712
Marken A.E. Verbeeck, Jack P.M. Elands, Lou F.M.H. de Leij, Charles H.C.M. Buys, Desmond Niall Carney, Gerold Bepler, Anton J.M. Roebroek, Wim J.M. van de Ven, J. Peter H. Burbach;
Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines.
Pathobiology 60:136-142(1992)

PubMed=9212023; DOI=10.1016/S0360-3016(97)00245-9
Marianne Krarup, Hans Skovgaard Poulsen, Mogens Spang-Thomsen;
Cellular radiosensitivity of small-cell lung cancer cell lines.
Int. J. Radiat. Oncol. Biol. Phys. 38:191-196(1997)

PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0
Lois M. Mulligan, Tineke Timmer, Stacey M. Ivanchuk, Barbara G. Campling, Leah C. Young, Pamela H. Rabbitts, Vasi Sundaresan, Robert M.W. Hofstra, Charis Eng;
Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinoma.
Genes Chromosomes Cancer 21:326-332(1998)

PubMed=9744504; DOI=10.1038/bjc.1998.553; PMCID=PMC2063065
Lars Damstrup, Bjorn Gunnar Rude Voldborg, Mogens Spang-Thomsen, Nils Brunner, Hans Skovgaard Poulsen;
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

PubMed=10408787; DOI=10.1097/00019606-199903000-00002
Vanessa M. Hayes, Wim Bleeker, Edwin Verlind, Tineke Timmer, Arend Karrenbeld, John T. Plukker, Munro Peter Marx, Robert M.W. Hofstra, Charles H.C.M. Buys;
Comprehensive TP53-denaturing gradient gel electrophoresis mutation detection assay also applicable to archival paraffin-embedded tissue.
Diagn. Mol. Pathol. 8:2-10(1999)

PubMed=12712436; DOI=10.1002/ijc.11106
Lasse Tengbjerg Hansen, Cecilia Lundin, Mogens Spang-Thomsen, Lone Norgard Petersen, Thomas Helleday;
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8212
Encyclopedic resources Wikidata; Q54835907
Polymorphism and mutation databases Cosmic; 2239120
Cosmic; 2648014
IARC_TP53; 11272
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18