Cellosaurus cell line D407 (CVCL

Cellosaurus D407 (CVCL_8183)

Cross-references
Cell line name	D407
Synonyms	D-407; D 407; D407 RPE; RPE D407
Accession	CVCL_8183
Resource Identification Initiative	To cite this cell line use: D407 (RRID:CVCL_8183)
Comments	Omics: Proteomics; 2DE-MS. Omics: Transcriptomics; Microarray. Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782. Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	12Y
Category	Spontaneously immortalized cell line
Web pages	Info; LRI; -; https://web.archive.org/web/20100714222342/http://www.lerner.ccf.org/eye/crabb/research/gel_d407_cell.php
Publications	PubMed=7706045 Alberta A. Davis, Paul S. Bernstein, Dean Bok, James Turner, Maurice Nachtigal, Richard C. Hunt; A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest. Ophthalmol. Vis. Sci. 36:955-964(1995) PubMed=14551534; PMCID=PMC2819117 Anna T. Rogojina, William E. Orr, Bong K. Song, Eldon E. Geisert Jr.; Comparing the use of Affymetrix to spotted oligonucleotide microarrays using two retinal pigment epithelium cell lines. Mol. Vis. 9:482-496(2003) PubMed=21074641; DOI=10.1016/j.jprot.2010.11.004; PMCID=PMC5173386 Hilal Arnouk, Hyunju Lee, Ruo-Nan Zhang, Hyewon Chung, Richard C. Hunt, Wan Jin Jahng; Early biosignature of oxidative stress in the retinal pigment epithelium. J. Proteomics 74:254-261(2011) PubMed=25177495; DOI=10.1155/2014/801787; PMCID=PMC4142280 Alla V. Kuznetsova, Alexander M. Kurinov, Maria A. Aleksandrova; Cell models to study regulation of cell transformation in pathologies of retinal pigment epithelium. J. Ophthalmol. 2014:801787.1-801787.18(2014)
Anatomy/cell type resources	BTO; BTO_0004595
Encyclopedic resources	Wikidata; Q54817226
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	14